Abstract : In the presence of Piperidine, the reaction of 4-Hydroxysalicylaldehyde with ethyl 3-oxobutanoate produced the compound 3-acetyl-7-hydroxychromen-2-one (1), which was subsequently cyclized with ammonium acetate to pyridine derivative (APHCP) (2). TLC (Thin Layer Chromatography), Melting level, Fourier-transform infrared spectroscopy, while Proton nuclear magnetic resonance had been utilized to describe the newly created substance. Pyridine derivative (APHCP) (2) is just a synthesized substance t